TDB–Cibacron Blue 3G-A

发表于2024年12月3日由上海金畔生物科技有限公司

CAS number: 84166-13-2

Cibacron Blue 3G-A is an anionic anthraquinone dye. It is commonly used as a ligand in affinity chromatography for the purification of proteins, enzymes and biopolymers.

Cibacron Blue 3G-A 是一种阴离子蒽醌染料。它通常用作亲和色谱中的配体，用于纯化蛋白质、酶和生物聚合物。

Structure
Cibacron Blue 3G-A dye consists of anthraquinone backbond link to phenyl, triazine, and phenyl rings interconnected by C-N bonds and adorn by amine and sulfate functional moieties.

结构
Cibacron Blue 3G-A 染料由蒽醌反键连接到苯基、三嗪和苯环组成，这些苯环通过 C-N 键相互连接，并由胺和硫酸盐官能团修饰。

Storage and stability
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Cibacron Blue 3G-A is stable under recommended storage conditions.

储存和稳定性
存放于阴凉处。将容器密封在干燥和通风良好的地方。 Cibacron Blue 3G-A 在推荐的储存条件下是稳定的。

Solubility
Cibacron Blue 3G-A is soluble in water.

溶解度
Cibacron Blue 3G-A 可溶于水。

Application
Cibacron Blue 3G-A has been employed in the textile industry for many years. It has shown tremendous protein binding capacity and can readily be immobilized on the polymer containing a hydroxyl group. Due to its aforementioned properties, it has been used as a ligand in affinity chromatography for the purification of proteins and enzymes. It was also reported to apply for the purification of biopolymers (e.g., interferons and albumins). Read more about application here.

应用
Cibacron Blue 3G-A 已在纺织工业中使用多年。它已显示出巨大的蛋白质结合能力，并且可以很容易地固定在含有羟基的聚合物上。由于其上述特性，它已被用作亲和层析中的配体，用于纯化蛋白质和酶。据报道，它还适用于生物聚合物（例如干扰素和白蛋白）的纯化。在此处阅读有关应用程序的更多信息。

Catalog no	Name	MW (Da)	Packsize
CBLUE	Cibacron Blue 3G-A	n/a	1g
CBLUE	Cibacron Blue 3G-A	n/a	5g

References

TDB–FITC (Fluorescein isothiocyanate)

发表于2024年12月3日由上海金畔生物科技有限公司

TDB–FITC (Fluorescein isothiocyanate)

Molecular Formula: C21H11NO5S

CAS Number isomer I: 3326-32-7
CAS Number isomer II: 18861-78-4

FITC (fluorescein isothiocyanate) is a derivative of fluorescein. It is the most widely used fluorescent probe for the preparation of conjugates of molecules from molecular biology or carbohydrate polymers such as dextran¹.

FITC（异硫氰酸荧光素）是荧光素的衍生物。它是最广泛使用的荧光探针，用于从分子生物学或碳水化合物聚合物（如葡聚糖1）制备分子偶联物。

Structure and physical properties
FITC exhibits an excitation maximum at λ = 495 nm and emission maximum at approximately λ = 519 nm. The color of the compound is yellow while the emitted light is green. There are two different isomers of FITC:

结构和物理特性
FITC 在 λ = 495 nm 处表现出最大激发，在大约 λ = 519 nm 处表现出最大发射。该化合物的颜色为黄色，而发出的光为绿色。 FITC 有两种不同的异构体：

Isomer I, also referred to as fluorescein 5-isothiocyanate or 5-FITC
Isomer II, also referred to as fluorescein 6-isothiocyanate or 6-FITC

The variation of the excitation and emission wavelengths among the two isomers of FITC is minor. FITC-functionalized biopolymers such as FITC-dextrans exhibit similar excitation and emission 0.

FITC 的两种异构体之间激发和发射波长的变化很小。 FITC 功能化的生物聚合物，如 FITC-葡聚糖，表现出类似的激发和发射 0。

Plot FITC — ***Figure 1. Excitation(orange) and emission (blue) spectrum of FITC isomer I.*** *The excitation maximum is 495 nm and the emission maximum is approximately 519 nm.*

Depending on the isomer, FITC contains an isothiocyanate group at either position 5 (isomer I) or position 6 (isomer 2) of the bottom benzene ring, see figure 2. Isothiocyanate easily reacts with nucleophiles such as amines under mild conditions. The compound is often used in the form of one of its two isomers or sometimes as mixture of the two.

根据异构体的不同，FITC 在底部苯环的第 5 位（异构体 I）或第 6 位（异构体 2）包含一个异硫氰酸酯基团，见图 2。异硫氰酸酯在温和条件下很容易与胺等亲核试剂反应。该化合物通常以其两种异构体之一的形式或有时以两种异构体的形式使用。

Storage and stability
Store at 0-8 ˚C in a tightly closed container when not in use. FITC is stable under recommended storage conditions.

储存和稳定性
不使用时，将其储存在 0-8 ˚C 的密闭容器中。 FITC 在推荐的储存条件下是稳定的。

Solubility
FITC is soluble in DMSO and DMF.

溶解度
FITC 可溶于 DMSO 和 DMF。

Applications

General FITC is commonly used for labeling antibodies² (IgG) and also in other immunological applications. It is also often used in flow cytometry, a technology frequently used by biologists to study cellular populations with high precision³.

应用

一般的FITC 通常用于标记抗体 2 (IgG) 以及其他免疫学应用。它也常用于流式细胞术，生物学家经常使用这种技术来高精度研究细胞群3。

FITC-dextran FITC-葡聚糖

The labelling of dextran with fluorescein via its FITC derivative was first described in a publication in 1973 by de Belder and Granath⁴. Now it is a long-established method for obtaining fluorescent labelled polysaccharides. FITC-functionalized polysaccharides such as FITC-dextrans are very useful for studying permeability and transport in a large variety of cells and tissues. This includes the intestinal⁵, neoplastic⁶– and ocular⁷ tissue as well as in research related to brain and neural system⁸. FITC-dextran and other FITC-conjugated polysaccharides can also be used to study the microcirculation, which can be described as the smallest circulation of blood in the microvessels. These are present within all organ tissues. FITC-dextrans have been used in studies of leukocyte adhesion, macromolecular leakage (see figure 3) and the leakage of microcirculation during ischemia/reperfusion ⁹. FITC-dextrans have also been used to study the intestinal mucosal microcirculation¹⁰.

de Belder 和 Granath 于 1973 年在出版物中首次描述了用荧光素通过其 FITC 衍生物标记葡聚糖。现在它是一种长期建立的获得荧光标记多糖的方法。 FITC 功能化多糖，如 FITC-葡聚糖，对于研究多种细胞和组织的渗透性和转运非常有用。这包括肠道 5、肿瘤 6 和眼 7 组织以及与大脑和神经系统相关的研究 8。 FITC-葡聚糖等FITC-共轭多糖也可用于研究微循环，可谓微血管中血液的最小循环。它们存在于所有器官组织中。 FITC-葡聚糖已用于研究白细胞粘附、大分子渗漏（见图 3）和缺血/再灌注过程中微循环的渗漏 9。FITC-葡聚糖也已用于研究肠粘膜微循环 10。

hamster cheek pouch injected with 150 kDa FITC-dextran_1 — **Figure 3. Hamster cheek pouch injected with 150 kDa FITC-dextran.** The picture was taken 1 min after injection.

pH Indicator pH指示剂

FITC and other fluorescent dyes have the ability of changing color in response to pH-changes. This can be utilized for measuring pH in living cells. Changes in cellular pH can reflect a range of physiological processes, including muscle contraction, endocytosis, cell proliferation, apoptosis, and ion transport¹¹.

Fluorescent pH-indicators can be either stand-alone-dyes, such as FITC, or dyes coupled to a macromolecule, such as FITC-dextran. The advantage of using fluorescent dextran derivatives is that the molecules can be accumulated in specific intracellular compartments¹². Compared to microelectrode techniques, fluorescent pH-indicators also have greater spatial sampling capability¹¹. Another advantage of the probes and indicators is that they don’t bind to cellular proteins¹².

FITC 和其他荧光染料具有响应 pH 值变化而改变颜色的能力。这可用于测量活细胞中的 pH 值。细胞 pH 值的变化可以反映一系列生理过程，包括肌肉收缩、内吞作用、细胞增殖、细胞凋亡和离子转运11。

荧光 pH 指示剂可以是独立染料，例如 FITC，也可以是与大分子偶联的染料，例如 FITC-葡聚糖。使用荧光葡聚糖衍生物的优点是分子可以在特定的细胞内隔室中积累。与微电极技术相比，荧光 pH 指标还具有更大的空间采样能力 11。探针和指示剂的另一个优点是它们不与细胞蛋白质结合。

Catalog no	Name	MW (Da)	Packsize
FITC	FITC (isomer I)	n/a	100mg
FITC	FITC (isomer I)	n/a	250mg
FITC	FITC (isomer I)	n/a	1g

FITC-products from TdB Labs

FITC (isomer I)
FITC -dextran
FITC -lysine-dextran
FITC-CM -dextran
FITC-CM -polysucrose
FITC-DEAE -dextran
FITC-DEAE -polysucrose
FITC -dextran sulfate
FITC -hydroxyethyl starch
FITC -inulin
FITC -polysucrose
FITC -Q-dextran
FITC -trehalose
Fluorescein Hyaluronic Acid

References

All publications

Fluorescein Isothiocyanate – an overview | ScienceDirect Topics. https://www.sciencedirect.com/topics/neuroscience/fluorescein-isothiocyanate.
The, T. H. & Feltkamp, T. E. W. Conjugation of fluorescein isothiocyanate to antibodies. Immunology 18, 865–873 (1970).
Picot, J., Guerin, C. L., Le Van Kim, C. & Boulanger, C. M. Flow cytometry: retrospective, fundamentals and recent instrumentation. Cytotechnology 64, 109–130 (2012).
de Belder, A. N. & Granath, K. Preparation and properties of fluorescein-labelled dextrans. Carbohydrate Research 30, 375–378 (1973).
Aden, K. et al. Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice. Gastroenterology 156, 145-159.e19 (2019).
Gerlowski, L. E. & Jain, R. K. Microvascular permeability of normal and neoplastic tissues. Microvasc. Res. 31, 288–305 (1986).
Elevated cAMP opposes (TNF-alpha)-induced loss in the barrier integrity of corneal endothelium. – Abstract – Europe PMC. https://europepmc.org/article/pmc/pmc2932488.
Hultström, D., Malmgren, L., Gilstring, D. & Olsson, Y. FITC-Dextrans as tracers for macromolecular movements in the nervous system. A freeze-drying method for dextrans of various molecular sizes injected into normal animals. Acta Neuropathol. 59, 53–62 (1983).
Svensjö, E. et al. Maxadilan, the Lutzomyia longipalpis vasodilator, drives plasma leakage via PAC1–CXCR1/2-pathway. Microvascular Research 83, 185–193 (2012).
Schmidt, C. et al. Confocal laser endomicroscopy reliably detects sepsis-related and treatment-associated changes in intestinal mucosal microcirculation. Br J Anaesth 111, 996–1003 (2013).
Han, J. & Burgess, K. Fluorescent indicators for intracellular pH. Chem. Rev. 110, 2709–2728 (2010).
Takahashi, S. et al. Development of a Series of Practical Fluorescent Chemical Tools To Measure pH Values in Living Samples. J. Am. Chem. Soc. 140, 5925–5933 (2018).

TDB–Stand-alone dyes 染料

发表于2024年12月3日由上海金畔生物科技有限公司

TDB–Stand-alone dyes 染料

TdB Labs are now launching a new set of stand-alone dyes; FITC (Fluorescein isothiocyanate) and Cibacron Blue 3G-A.

TdB Labs 现在推出了一套新的独立染料； FITC（异硫氰酸荧光素）和 Cibacron Blue 3G-A。

Special introductory price! Launching discount for a limited time period.

Applications 应用

FITC (Fluorescein isothiocyanate) is a derivative of fluorescein. FITC exhibits an excitation maximum at λ = 495 nm and emission maximum at approximately λ = 519 nm. FITC can be easily used as labelling agent of various substrates such as proteins or polysaccharides. Isothiocyanate easily reacts with nucleophiles such as amines under mild conditions. FITC can also be used in flow cytometry.

FITC（异硫氰酸荧光素）是荧光素的衍生物。 FITC 在 λ = 495 nm 处表现出最大激发，在大约 λ = 519 nm 处表现出最大发射。 FITC 可以很容易地用作各种底物如蛋白质或多糖的标记剂。异硫氰酸酯在温和的条件下很容易与亲核试剂如胺反应。 FITC 也可用于流式细胞术。

Cibacron Blue 3G-A is an anionic anthraquinone dye. It is as a ligand in affinity chromatography for the purification of proteins, enzymes and biopolymers. Cibacron Blue 3G-A has also been employed in the textile industry for many years. It has shown tremendous protein binding capacity and can readily be immobilized on polymers containing a hydroxyl group.

Cibacron Blue 3G-A 是一种阴离子蒽醌染料。它是亲和色谱中的配体，用于纯化蛋白质、酶和生物聚合物。 Cibacron Blue 3G-A 也已在纺织工业中使用多年。它已显示出巨大的蛋白质结合能力，并且可以很容易地固定在含有羟基的聚合物上。

Products

FITC (Fluorescein isothiocyanate)

CAS Number: 3326-32-7

FITC (isomer I) is a derivative of fluorescein. FITC exhibits an excitation maximum at λ = 495 nm and emission maximum at approximately λ = 519 nm.

Cibacron Blue 3G-A

CAS Number: 84166-13-2

Cibacron Blue 3GA is an anionic anthraquinone dye. It is as a ligand in affinity chromatography for the purification of proteins, enzymes and biopolymers.

TDB–Tetramethylrhodamine Hyaluronic Acid 四甲基罗丹明透明质酸

发表于2024年12月3日由上海金畔生物科技有限公司

TDB–Tetramethylrhodamine Hyaluronic Acid 四甲基罗丹明透明质酸

Hyaluronic acid (HA) can be obtained from various sources, for example rooster combs orStreptococcus equi. We can supply derivatives of either of these qualities labelled with tetramethylrhodamine (T-HA). All batches are checked for molecular weight, degree of substitution, loss on drying and free TRITC. TdB Labs can produce T-HA with a molecular weight of approximately 1.5 MDa. T-HA is supplied as a pink powder.

透明质酸 (HA) 可以从各种来源获得，例如鸡冠或马链球菌。我们可以提供标有四甲基罗丹明 (T-HA) 的这些品质的衍生物。检查所有批次的分子量、取代度、干燥失重和游离 TRITC。 TdB Labs 可以生产分子量约为 1.5 MDa 的 T-HA。 T-HA 以粉红色粉末形式提供。

Structure 结构
Hyaluronic acid is a polysaccharide composed of alternating β(1-3) glucuronide and β(1-4) glucosaminide units derived from Streptococcus equi. The hyaluronic acid is labelled with amino-tetramethylrhodamine. The degree of substitution lies between 0.001 and 0.008. The labelling procedures do not lead to depolymerisation of the HA.

透明质酸是一种多糖，由来自马链球菌的交替的 β(1-3) 葡糖苷酸和 β(1-4) 葡糖胺单位组成。透明质酸用氨基四甲基罗丹明标记。取代度介于 0.001 和 0.008 之间。标记程序不会导致 HA 解聚。

Spectral data
T-HA has an excitation maximum at 552 nm and an emission maximum at 576 nm.

光谱数据
T-HA 在 552 nm 处具有最大激发，在 576 nm 处具有最大发射。

Storage and stability
T-HA is stable for more than 6 years when stored dry in well-sealed containers.

储存和稳定性
在密封良好的容器中干燥储存时，T-HA 可稳定保存 6 年以上。

Solubility
T-HA dissolves readily in water.

溶解度
T-HA 易溶于水。

Application
T-HA have been used to e.g. investigate invasive growth into brain tissue. Read more about applications here.

应用
T-HA 已被用于例如研究侵入性生长进入脑组织。在此处阅读有关应用程序的更多信息。

References

Pusch, A. et al. CD44 and hyaluronan promote invasive growth of B35 neuroblastoma cells into the brain. Biochimica et Biophysica Acta (BBA) – Molecular Cell Research 1803, 261–274 (2010)
Kaminski, T., Siebrasse, J.-P., Gieselmann, V., Kubitscheck, U., Kappler, J. Imaging and tracking of single hyaluronan molecules diffusing in solution. Glycoconjugate Journal 25(6), 555-560 (2008).

TDB–Antonia Red™ Dextrans Antonia Red™ 葡聚糖

发表于2024年12月3日由上海金畔生物科技有限公司

TDB–Antonia Red™ Dextrans Antonia Red™ 葡聚糖

Antonia Red™ is a red-shifted dye with an absorbance maximum at 583 and an emission wavelength of 602 nm. All batches are carefully controlled for molecular weight, appearance, solubility, degree of substitution, fluorescence and free dye. TdB Labs produce Antonia Red-dextran from 4 kDa to 150 kDa. Antonia Red-dextrans are supplied as a purple powder.

Antonia Red™ 是一种红移染料，最大吸光度为 583，发射波长为 602 nm。所有批次的分子量、外观、溶解度、取代度、荧光和游离染料都经过仔细控制。 TdB Labs 生产 4 kDa 至 150 kDa 的 Antonia Red-dextran。 Antonia Red-dextrans 以紫色粉末形式提供。

Structure
Antonia Red™-dextran are synthesised from well-characterised dextran fractions derived from Leuconostoc mesenteroides. The dextran fractions are then labelled with Antonia Red. The degree of substitution lies between 0.001-0.01.

结构
Antonia Red™-葡聚糖由来自肠系膜明串珠菌的充分表征的葡聚糖级分合成。然后用安东尼红标记葡聚糖级分。取代度在0.001-0.01之间。

Spectral data
Antonia Red™-dextran has an absorbance maximum at 583 nm and an emission wavelength of 602 nm in borate buffer at pH 9.0.

光谱数据
Antonia Red™-葡聚糖在 pH 9.0 的硼酸盐缓冲液中的最大吸光度为 583 nm，发射波长为 602 nm。

Storage and stability
Antonia Red™ dextran is stable for more than 6 years when stored dry in well-sealed containers at ambient temperature

储存和稳定性
Antonia Red™ 葡聚糖在环境温度下干燥储存在密封良好的容器中时可稳定保存 6 年以上

Solubility
Antonia Red™-dextran dissolves readily in water.

溶解度
Antonia Red™-葡聚糖易溶于水。

Application
Antonia Red™-dextran is mainly used for studying permeability and microcirculation. It can also be used as a molecular size marker, for studies of drug delivery and more. Antonia Red shows bright fluorescence, has good photo- and chemical stability and is non-pH dependent. Read more about applications here.

应用
Antonia Red™-葡聚糖主要用于研究渗透性和微循环。它还可以用作分子大小标记，用于药物递送研究等。 Antonia Red 显示出明亮的荧光，具有良好的光和化学稳定性，并且不依赖于 pH 值。在此处阅读有关应用程序的更多信息。

References 参考文献

Gustafsson, S. et al. Blood-brain barrier integrity in a mouse model of Alzheimer’s disease with or without acute 3D6 immunotherapy. Neuropharmacology 143, 1–9 (2018).

TDB–Hyaluronic acid derivatives 透明质酸衍生物

发表于2024年12月3日由上海金畔生物科技有限公司

TDB–Hyaluronic acid derivatives 透明质酸衍生物

Hyaluronic acid (HA) coupled to fluorescent dyes is manufactured and offered at TdB Labs. The products exhibit high photo-and chemical stability and bright fluorescence. TdB Labs can produce fluorescent HA derivatives with a molecular weight of approximately 6 MDa. Our high-quality fluorescent Hyaluronic acid derivatives offer:

与荧光染料偶联的透明质酸 (HA) 由 TdB 实验室制造和提供。该产品具有高光稳定性和化学稳定性以及明亮的荧光。 TdB Labs 可以生产分子量约为 6 MDa 的荧光 HA 衍生物。我们的高品质荧光透明质酸衍生物提供：

Bright fluorescence
Red-shifted or Green-shifted emission and excitation
Good photo- and chemical stability
pH dependence
Particle-free formulations
Excellent water solubility

明亮的荧光
红移或绿移发射和激发
良好的光和化学稳定性
pH依赖性
无颗粒配方
优异的水溶性

Derivatives
TdB Labs offer Hyaluronic acid coupled to Fluorescein or to Tetramethylrhodamine.

衍生品
TdB Labs 提供与荧光素或四甲基罗丹明偶联的透明质酸。

Applications
Fluorescent derivatives of hyaluronic acid are mainly used for studying of the hyaluronan uptake into various tissues, as well as studying ivasive growth of cancer in brain and other organs. Read more about application here.

应用
透明质酸的荧光衍生物主要用于研究透明质酸吸收到各种组织中，以及研究大脑和其他器官中癌症的血管生长。在此处阅读有关应用程序的更多信息。

Fluorescein Hyaluronic Acid

As a leading producer of fluorescent polysaccharides, we have over the years received requests for Hyaluronic acid coupled to Fluorescein.

荧光素透明质酸

作为荧光多糖的领先生产商，多年来我们收到了对与荧光素偶联的透明质酸的需求。

Tetramethylrhodamine Hyaluronic Acid

As a leading producer of fluorescent polysaccharides, we have over the years received requests for Hyaluronic acid coupled to Tetramethylrhodamine.

四甲基罗丹明透明质酸

作为荧光多糖的领先生产商，多年来我们收到了对与四甲基罗丹明偶联的透明质酸的需求。

TDB–Polysucrose 聚蔗糖

发表于2024年12月3日由上海金畔生物科技有限公司

TDB–Polysucrose 聚蔗糖

Dextran, epichlorohydrin cross-linked polymer

葡聚糖、表氯醇交联聚合物

CAS number: 26873-85-8

Polysucrose is supplied as a white powder which is freely soluble in water and electrolyte solutions. Many investigators have considered polysucrose to be a suitable molecule for studying glomerular physiology since it is biocompatible and not readily degraded in the blood stream. Further it has conformational properties more like proteins. Polysucrose (and particularly FITC-and TRITC-labelled polysucrose) have been used extensively in studies of vascular permeability, in particular glomerular permselectivity and has been reviewed. Polysucroses have been used for many decades for such purposes as gradient centrifugation of cells and organelles, nucleic acid hybridization, as a hapten carrier, concentration dialysis, to support growth of cell lines and phase partitioning.

聚蔗糖以白色粉末形式提供，可自由溶于水和电解质溶液。许多研究人员认为聚蔗糖是研究肾小球生理学的合适分子，因为它具有生物相容性并且不容易在血流中降解。此外，它具有更像蛋白质的构象特性。聚蔗糖（尤其是 FITC 和 TRITC 标记的聚蔗糖）已广泛用于血管通透性研究，特别是肾小球渗透选择性研究，并已进行了审查。几十年来，聚蔗糖已被用于细胞和细胞器的梯度离心、核酸杂交、作为半抗原载体、浓缩透析等目的，以支持细胞系的生长和相分配。

Catalog no	Name	MW (Da)	Packsize
P20	Polysucrose 20	20000	1g
P40	Polysucrose 40	40000	1g
P50	Polysucrose 50	50000	1g
P1000	Polysucrose 1000	1000000	1g

TDB–Q-dextran Q-葡聚糖

发表于2024年12月3日由上海金畔生物科技有限公司

TDB–Q-dextran Q-葡聚糖

O-Trimethylammonium-glycidyl-dextran

O-三甲基铵-缩水甘油基-葡聚糖

CAS number: not available

Q-dextran is supplied as a coarse white powder and is readily soluble in water. The nitrogen content is approx.

2% (by elemental analysis) which corresponds to approximately one quaternary ammonium group for every four

glucose units. The nitrogen content is 1.5 – 2.5%. Unlike DEAE-dextrans, Q-dextrans will be charged over a wide

range of pH (pH 4-10). They also have a much stronger net charge and thus give enhanced responses in systems

where this effect is important. Polycati

Q-dextran is a polycationic derivative of dextran. These derivatives are distinct from DEAE-dextrans in that they only contain quaternary amine groups. Unlike DEAE-dextrans, Q-dextrans will be charged over a wide range of pH (pH 4-10). Q-dextrans will also have a much stronger net charge than corresponding DEAE-dextrans. All batches are checked for molecular weight, degree of substitution and loss on drying. TdB Labs produce Q-dextran from 4 kDa to 150 kDa. Q-dextrans are supplied as a white powder.

Can’t find what you are looking for? We can always produce a customised product for you. Read more here.

CAS号：不可用

Q-葡聚糖以粗白色粉末形式提供，易溶于水。氮含量约为。

2%（通过元素分析），相当于每四个季铵基团大约一个

葡萄糖单位。氮含量为 1.5 – 2.5%。与 DEAE-dextrans 不同，Q-dextrans 将被收取广泛的费用

pH 范围（pH 4-10）。它们还具有更强的净电荷，从而在系统中提供增强的响应

这种效果很重要。波利卡蒂

Q-葡聚糖是葡聚糖的聚阳离子衍生物。这些衍生物与 DEAE-葡聚糖的不同之处在于它们仅包含季胺基团。与 DEAE-葡聚糖不同，Q-葡聚糖将在很宽的 pH 值范围内（pH 4-10）带电。 Q-dextrans 的净电荷也比相应的 DEAE-dextrans 强得多。检查所有批次的分子量、取代度和干燥损失。 TdB Labs 可生产 4 kDa 至 150 kDa 的 Q-葡聚糖。 Q-葡聚糖以白色粉末形式提供。

不能找到你想要的？我们可以随时为您生产定制产品。在这里阅读更多。

Structure
Q-dextrans are synthesised by reacting dextran fractions with 2,3-epoxypropyltrimethylammonium chloride. The nitrogen content is approximately 2% which corresponds to one quaternary ammonium group for every four glucose units.

Storage and stability
Q-dextran is stable for more than 6 years when stored dry in well-sealed containers at ambient temperature.

Solubility
Q-dextran dissolves readily in water.

Application
Polycationic products exhibit a wide variety of effects in cellular systems and are of interest as adjuvants in vaccines. Q-dextran has a much stronger net charge than corresponding DEAE-dextrans and will thus give enhanced responses in systems where this effect is important. Read more about application here.

结构
Q-葡聚糖是通过葡聚糖组分与 2,3-环氧丙基三甲基氯化铵反应合成的。氮含量约为 2%，对应于每四个葡萄糖单位一个季铵基团。

储存和稳定性
Q-葡聚糖在环境温度下在密封良好的容器中干燥储存时可稳定保存 6 年以上。

溶解度
Q-葡聚糖易溶于水。

应用
聚阳离子产品在细胞系统中表现出多种作用，并且在疫苗中作为佐剂受到关注。 Q-葡聚糖的净电荷比相应的 DEAE-葡聚糖强得多，因此在这种效应很重要的系统中会增强响应。在此处阅读有关应用程序的更多信息。

Catalog no	Name	MW (Da)	Packsize
QD4	Q-dextran 4	4000	10g
QD4	Q-dextran 4	4000	100g
QD10	Q-dextran 10	10000	10g
QD10	Q-dextran 10	10000	100g
QD20	Q-dextran 20	20000	10g
QD20	Q-dextran 20	20000	100g
QD70	Q-dextran 70	70000	10g
QD70	Q-dextran 70	70000	100g
QD150	Q-dextran 150	150000	10g
QD150	Q-dextran 150	150000	100g

References

TDB–Blue Dextrans 蓝色葡聚糖

发表于2024年12月3日由上海金畔生物科技有限公司

TDB–Blue Dextrans 蓝色葡聚糖

CAS number: 87915-38-6

Blue dextran 2000 has long been used as a void volume marker in chromatography

and Blue-dextran gel conjugates for chromatography have been available for many

years (e.g. see GE Healthcare Life Sciences; Size Exclusion Chromatography; Princi

ples and Methods). Other important areas of research,

Blue dextran 2000 长期以来一直被用作色谱中的空隙体积标记

和用于色谱的蓝色葡聚糖凝胶偶联物已可用于许多

年（例如，参见 GE Healthcare Life Sciences；尺寸排阻色谱；Princi

ples 和方法）。其他重要的研究领域，

where blue-dextrans have been used, are:

Studies on lysosomal activity
Endothelial cell permeability
Bovine sperm permeability
Cornea permeability
Flow studies in lung
Cerebro-permeability
Binding of proteins and enzymes to blue dextran.

使用蓝色葡聚糖的地方是：

溶酶体活性研究
内皮细胞通透性
牛精子通透性
角膜渗透性
肺中的流动研究
脑渗透性
蛋白质和酶与蓝色葡聚糖的结合。

Spectral data: The blue chromophore has an absorbance maximum at 621.5 nm

CAS Number: 87915-38-6

Blue dextrans are synthesised from controlled dextran fractions by reacting with Cibacron blue F3GA. After purification from non-bound dye, products are controlled for molecular weight, solubility, degree of substitution, free dye and loss on drying. TdB Labs offer blue dextran in a wide variety of molecular weights, ranging from 5 kDa to 2000 kDa.

蓝色葡聚糖是通过与 Cibacron blue F3GA 反应从受控的葡聚糖级分合成的。从非结合染料中纯化后，对产品的分子量、溶解度、取代度、游离染料和干燥失重进行控制。 TdB Labs 提供各种分子量的蓝色葡聚糖，范围从 5 kDa 到 2000 kDa。

Structure
Dextran is a polysaccharide derived from the bacterium Leuconostoc mesenteroides B512F; and consists of an α-D-(1 – 6) linear glucan with a low content (ca. 5%) of side chains linked to 3-carbon of glucose. The dextran is then labelled with Cibacron blue F3GA.

结构
葡聚糖是一种源自肠系膜明串珠菌 B512F 的多糖；由 α-D-(1 – 6) 线性葡聚糖组成，侧链含量低（约 5%），与葡萄糖的 3-碳相连。然后用 Cibacron blue F3GA 标记葡聚糖。

Storage and stability
Blue dextrans are stable for more than 6 years when stored dry in well-sealed containers at ambient temperature

储存和稳定性
蓝色葡聚糖在环境温度下干燥储存在密封良好的容器中时可稳定保存 6 年以上

Solubility
Blue dextran dissolves freely in water.

溶解度
蓝色葡聚糖在水中自由溶解。

Applications
Blue dextran has long been used as a void volume marker in chromatography. Blue dextran can also be used as a molecular marker. Read more about application here.

应用
长期以来，蓝色葡聚糖一直被用作色谱中的空隙体积标记。蓝色葡聚糖也可用作分子标记。在此处阅读有关应用程序的更多信息。

Catalog no	Name	MW (Da)	Packsize
BD5	Blue dextran 5	5000	1g
BD5	Blue dextran 5	5000	10g
BD10	Blue dextran 10	10000	1g
BD10	Blue dextran 10	10000	10g
BD20	Blue dextran 20	20000	1g
BD20	Blue dextran 20	20000	10g
BD40	Blue dextran 40	40000	1g
BD40	Blue dextran 40	40000	10g
BD70	Blue dextran 70	70000	1g
BD70	Blue dextran 70	70000	10g
BD110	Blue dextran 110	110000	1g
BD110	Blue dextran 110	110000	10g
BD500	Blue dextran 500	500000	1g
BD500	Blue dextran 500	500000	10g
BD2000	Blue dextran 2000	2000000	1g
BD2000	Blue dextran 2000	2000000	10g

References

Click to view publications

Beugeling, M. et al. The mechanism behind the biphasic pulsatile drug release from physically mixed poly(dl-lactic(-co-glycolic) acid)-based compacts. International Journal of Pharmaceutics 551, 195–202 (2018).
Russo, D. et al. Direct photolysis of benzoylecgonine under UV irradiation at 254nm in a continuous flow microcapillary array photoreactor. Chemical Engineering Journal 283, 243–250 (2016).
Vagenende, V., Ching, T.-J., Chua, R.-J., Jiang, Q. Z. & Gagnon, P. Self-assembly of lipopolysaccharide layers on allantoin crystals. Colloids and Surfaces B: Biointerfaces 120, 8–14 (2014).

Cosmobio抗体-Anti SETDB1

发表于2024年7月15日由上海金畔生物科技有限公司

Anti SETDB1

品牌： Cosmo Bio

产品货号： PRX-MKA0067AF

规格： 50 UG

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Anti SETDB1
保存温度:

-20C
运输温度:

dry ice

Cosmo Bio产品分类：仪器(Instruments)、细胞融合、转染、培养(Cell Fusion, Transfection, Culture)、体外翻译(In vitro Translation)、抗体(Antibodies)、检测试剂盒(ELISA & Detection Kits ELISA)、生物医学相关(Biomedical)、蛋白质、多肽&糖类(Proteins, Peptides & Sugars)、化学试剂(Chemicals)、分子生物(DNA Molecular Biology) .
更多产品请访问Cosmo Bio官网或者咨询我们获取更多相关产品信息。

TdB Labs代理,FITC Isomer I

发表于2024年3月11日由上海金畔生物科技有限公司

中文名称

FITC Isomer I

英文名字

英文名字

Cibacron Blue 3G-A

供应商

TdB Labs

产品货号

TDB-CBlue-5g

Cibacron 蓝色 3G-A(Cibacron Blue 3G-A)，CAS Number: 84166-13-2；分子量MW (kDa)：

TdB Labs代理,Cibacron 蓝色 3G-A产品的描述详情可查看TdB Labs厂家提供的产品说明书。更多产品信息，欢迎咨询微信同号18301939375，部分现货，期货货期3-4周。

TdB Labs提供FITC、TRITC、ATTO™染料、Antonia Red™荧光染料的葡聚糖衍生物。还提供葡聚糖硫酸盐的不同变体，包括用于结肠炎的葡聚糖硫酸钠（DSS）。TdB Labs产品广泛应用于生命科学领域，从渗透性研究、细胞保存和动物研究到临床产品加工的应用。

本网站可提供的所有产品和服务均不得用于人体或动物的临床诊断或治疗，仅可用于科研等非医疗目的。

TdB Labs代理,Cibacron 蓝色 3G-A

发表于2024年3月11日由上海金畔生物科技有限公司

中文名称

英文名字

Polysucrose 20

供应商

TdB Labs

产品货号

TDB-P20-1g

聚蔗糖 20(Polysucrose 20)，CAS Number: 26873-85-8；分子量MW (kDa)：20

TdB Labs代理,聚蔗糖 20产品的描述详情可查看TdB Labs厂家提供的产品说明书。更多产品信息，欢迎咨询微信同号18301939375，部分现货，期货货期3-4周。

TdB Labs提供FITC、TRITC、ATTO™染料、Antonia Red™荧光染料的葡聚糖衍生物。还提供葡聚糖硫酸盐的不同变体，包括用于结肠炎的葡聚糖硫酸钠（DSS）。TdB Labs产品广泛应用于生命科学领域，从渗透性研究、细胞保存和动物研究到临床产品加工的应用。

本网站可提供的所有产品和服务均不得用于人体或动物的临床诊断或治疗，仅可用于科研等非医疗目的。