AOAA Hemihydrochloride 氨氧基乙酸半盐酸盐


描述

AOAA Hemihydrochloride 氨氧基乙酸半盐酸盐

 

产品标签

AOAA Hemihydrochloride 氨氧基乙酸半盐酸盐;AOA Hemihydrochloride;WSP-1 (Washington State Probe-1);WSP-5;CBS抑制剂; GABA转氨酶抑制剂;CAS NO. 2921-14-4;

产品信息

产品名称

产品编号 规格         价格(元)

Aminooxyacetic Acid Hemihydrochloride (AOAA Hemihydrochloride)

氨氧基乙酸半盐酸盐

MX5314-500MG   

500mg 283
MX5314-1G 1g

423

MX5314-5G 5g

993

产品描述

氨氧基乙酸半盐酸盐(Aminooxyacetic Acid Hemihydrochloride, AOAA Hemihydrochloride)是GABA转氨酶抑制剂(Ki= 9.16μM),诱导大脑内GABA累积[1]。AOAA还能抑制胱硫醚β合成酶(CBS)和胱硫醚γ裂解酶(CSE)活性,IC50分别是8.5μM和1.1μM[2]。AOAA(100mg/kg)降低GABA转氨酶活性,不会对谷氨酸脱羧酶(GAD)活性产生影响,并且能提高大鼠大脑所有区域的GABA水平[3]。AOAA(13mg/kg)还能减低小鼠大脑的GABA转氨酶活性,以及增加GABA水平。AOAA抑制3-巯基丙酸、马钱子碱和戊四氮唑诱导的小鼠癫痫发作,ED50s分别是53、130和85mg/kg,然而,AOAA在烟囱试验中呈现神经毒性(ED50= 62mg/kg),且对小鼠有致命性(LD50=105mg/kg)[4]。AOAA还普遍用作苹果酸-天冬氨酸穿梭(Malate-aspartate shuttle, MAS)抑制剂,抑制C6胶质细胞的胞内ATP水平和改变细胞周期,还能减少糖酵解速率、胞外乳酸和丙酮酸水平[5]。

产品特性

同义名:Carboxymethoxylamine hemihydrochloride, AOAA hemihydrochloride, AOA hemihydrochloride, Aminooxyacetate hemihydrochloride; Aminooxyacetic Acid (hydrochloride);羧甲氧基胺半盐酸盐;羧基甲氧基胺半盐酸盐;氨氧基乙酸半盐酸盐;
CAS NO:2921-14-4 化学名:2-(aminooxy)-acetic acid hemihydrochloride
分子式:C2H5NO3• 1/2HCl

分子量:109.3

纯度:≥95%

外观:固体

溶解性:溶于DMSO(≥10mg/ml)、H2O(≥10mg/ml)、不溶于乙醇
化学结构式:

保存与运输方法

保存:-20℃干燥保存,至少2年有效。

运输:室温运输。

注意事项

1)本品并非商业化的临床药物,仅用作科研用途,不得用作临床诊断或治疗,不得用于食品或药品,绝对禁止用在人身上。

2)为了您的安全和健康,请穿实验服并戴一次性手套操作。

储存液制备

         质量

溶剂体积

浓度

1mg 5mg 10mg
1mM 9.1491 mL 45.7457 mL 91.4913 mL
5mM 1.8298 mL 9.1491 mL 18.2983 mL
10mM 0.9149 mL 4.5746 mL 9.1491 mL

【温馨提示】:请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。储备液置于-80°C密封避光干燥保存,约6个月有效;-20°C密封避光干燥保存,约1个月有效。

使用方法【源自文献,仅作参考】

文献1,Yang B, Su Y, Han S, Chen R, Sun R, Rong K, Long F, Teng H, Zhao J, Liu Q, Qin A. Aminooxyacetic acid hemihydrochloride inhibits osteoclast differentiation and bone resorption by attenuating oxidative phosphorylation. Front Pharmacol. 2022 Sep 30;13:980678. doi: 10.3389/fphar.2022.980678. PMID: 36249744; PMCID: PMC9561130.

体外研究(In Vitro Assay):

细胞类型(Cell type):Bone marrow-derived macrophages (BMMs)

配制方法(Formulation):AOAA was dissolved in phosphate-buffered saline at a concentration of 20 mM at−20°C, and further diluted to working concentration using culture medium.

实验方法(Cell viability assay):BMMs (7 × 103cells/well) were seeded into 96-well plates and cultured in complete α-MEM containing 30 ng/ml M-CSF andAOAA (0, 0.1, 0.2, 0.3, 0.4, and 0.5 mM) for 48 and 96 h.CCK-8 was used to measure cell viability.

体内研究(In Vivo Assay):

动物模型(Animal Model):Ovariectomized mouse model

实验方法(Assay):Twenty-four C57BL/6J mice (females, 11-week-old) were randomly divided into four groups containing six mice each: sham (injected PBS), OVX + PBS (injected PBS), OVX + estrogen (injected 100 ng/kg E2), and OVX + AOAA (injected 5 mg/kg AOAA). The mice were anesthetized with 3% tribromoethanol; next, both the ovaries of all mice except those in the sham group were surgically excised.A week later, the mice received intraperitoneal injections of PBS, E2, or AOAA every 2 days for 6 weeks.

文献2,Yan, J. et al. Inhibition of cystathionine β-synthetase suppresses sodium channel activities of dorsal root ganglion neurons of rats with lumbar disc herniation. Sci. Rep. 6, 38188; doi: 10.1038/srep38188 (2016).

体内研究(In Vivo Assay):

动物模型(Animal Model):LDH rats

实验方法(Assay):Immediately after resolved in NS,AOAA was injected intrathecally at 10μg/kg body weight, once daily for 7 consecutive days. Same volume of NS was used as control.L5-6DRGs from LDH rats after AOAA treatment were collected either for measurement of NaV1.7 and NaV1.8 expression or for patch clamping studies.

 

参考文献

[1] Wallach, D.P. Studies on the GABA pathway. I. The inhibition of γ-aminobutyric acid-α-ketoglutaric acid transaminase in vitro and in vivo by U-7524 (amino-oxyacetic acid). Biochem. Pharmacol. 5(4), 323-331 (1961).

[2] Asimakopoulou, A., Panopoulos, P., Chasapis, C.T., et al. Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE). Br. J. Pharmacol. 169(4), 922-932 (2013).

[3] Löscher, W., Hönack, D., and Gramer, M. Use of inhibitors of gamma-aminobutyric acid (GABA) transaminase for the estimation of GABA turnover in various brain regions of rats: A reevaluation of aminooxyacetic acid. J. Neurochem. 53(6), 1737-1750 (1989)

[4]Löscher, W. A comparative study of the pharmacology of inhibitors of GABA-metabolism. Naunyn Schmiedebergs Arch. Pharmacol. 315(2), 119-128 (1980).

[5] Wang C., Chen H., Zhang M., Zhang J., Wei X., Ying W. (2016). Malate-aspartate shuttle inhibitor aminooxyacetic acid leads to decreased intracellular ATP levels and altered cell cycle of C6 glioma cells by inhibiting glycolysis. Cancer Lett. 378, 1–7. 10.1016/j.canlet.2016.05.001

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AOAA Hemihydrochloride 氨氧基乙酸半盐酸盐


描述

AOAA Hemihydrochloride 氨氧基乙酸半盐酸盐

 

产品标签

AOAA Hemihydrochloride 氨氧基乙酸半盐酸盐;AOA Hemihydrochloride;WSP-1 (Washington State Probe-1);WSP-5;CBS抑制剂; GABA转氨酶抑制剂;CAS NO. 2921-14-4;

产品信息

产品名称

产品编号 规格         价格(元)

Aminooxyacetic Acid Hemihydrochloride (AOAA Hemihydrochloride)

氨氧基乙酸半盐酸盐

MX5314-500MG   

500mg 283
MX5314-1G 1g

423

MX5314-5G 5g

993

产品描述

氨氧基乙酸半盐酸盐(Aminooxyacetic Acid Hemihydrochloride, AOAA Hemihydrochloride)是GABA转氨酶抑制剂(Ki= 9.16μM),诱导大脑内GABA累积[1]。AOAA还能抑制胱硫醚β合成酶(CBS)和胱硫醚γ裂解酶(CSE)活性,IC50分别是8.5μM和1.1μM[2]。AOAA(100mg/kg)降低GABA转氨酶活性,不会对谷氨酸脱羧酶(GAD)活性产生影响,并且能提高大鼠大脑所有区域的GABA水平[3]。AOAA(13mg/kg)还能减低小鼠大脑的GABA转氨酶活性,以及增加GABA水平。AOAA抑制3-巯基丙酸、马钱子碱和戊四氮唑诱导的小鼠癫痫发作,ED50s分别是53、130和85mg/kg,然而,AOAA在烟囱试验中呈现神经毒性(ED50= 62mg/kg),且对小鼠有致命性(LD50=105mg/kg)[4]。AOAA还普遍用作苹果酸-天冬氨酸穿梭(Malate-aspartate shuttle, MAS)抑制剂,抑制C6胶质细胞的胞内ATP水平和改变细胞周期,还能减少糖酵解速率、胞外乳酸和丙酮酸水平[5]。

产品特性

同义名:Carboxymethoxylamine hemihydrochloride, AOAA hemihydrochloride, AOA hemihydrochloride, Aminooxyacetate hemihydrochloride; Aminooxyacetic Acid (hydrochloride);羧甲氧基胺半盐酸盐;羧基甲氧基胺半盐酸盐;氨氧基乙酸半盐酸盐;
CAS NO:2921-14-4 化学名:2-(aminooxy)-acetic acid hemihydrochloride
分子式:C2H5NO3• 1/2HCl

分子量:109.3

纯度:≥95%

外观:固体

溶解性:溶于DMSO(≥10mg/ml)、H2O(≥10mg/ml)、不溶于乙醇
化学结构式:

保存与运输方法

保存:-20℃干燥保存,至少2年有效。

运输:室温运输。

注意事项

1)本品并非商业化的临床药物,仅用作科研用途,不得用作临床诊断或治疗,不得用于食品或药品,绝对禁止用在人身上。

2)为了您的安全和健康,请穿实验服并戴一次性手套操作。

储存液制备

         质量

溶剂体积

浓度

1mg 5mg 10mg
1mM 9.1491 mL 45.7457 mL 91.4913 mL
5mM 1.8298 mL 9.1491 mL 18.2983 mL
10mM 0.9149 mL 4.5746 mL 9.1491 mL

【温馨提示】:请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。储备液置于-80°C密封避光干燥保存,约6个月有效;-20°C密封避光干燥保存,约1个月有效。

使用方法【源自文献,仅作参考】

文献1,Yang B, Su Y, Han S, Chen R, Sun R, Rong K, Long F, Teng H, Zhao J, Liu Q, Qin A. Aminooxyacetic acid hemihydrochloride inhibits osteoclast differentiation and bone resorption by attenuating oxidative phosphorylation. Front Pharmacol. 2022 Sep 30;13:980678. doi: 10.3389/fphar.2022.980678. PMID: 36249744; PMCID: PMC9561130.

体外研究(In Vitro Assay):

细胞类型(Cell type):Bone marrow-derived macrophages (BMMs)

配制方法(Formulation):AOAA was dissolved in phosphate-buffered saline at a concentration of 20 mM at−20°C, and further diluted to working concentration using culture medium.

实验方法(Cell viability assay):BMMs (7 × 103cells/well) were seeded into 96-well plates and cultured in complete α-MEM containing 30 ng/ml M-CSF andAOAA (0, 0.1, 0.2, 0.3, 0.4, and 0.5 mM) for 48 and 96 h.CCK-8 was used to measure cell viability.

体内研究(In Vivo Assay):

动物模型(Animal Model):Ovariectomized mouse model

实验方法(Assay):Twenty-four C57BL/6J mice (females, 11-week-old) were randomly divided into four groups containing six mice each: sham (injected PBS), OVX + PBS (injected PBS), OVX + estrogen (injected 100 ng/kg E2), and OVX + AOAA (injected 5 mg/kg AOAA). The mice were anesthetized with 3% tribromoethanol; next, both the ovaries of all mice except those in the sham group were surgically excised.A week later, the mice received intraperitoneal injections of PBS, E2, or AOAA every 2 days for 6 weeks.

文献2,Yan, J. et al. Inhibition of cystathionine β-synthetase suppresses sodium channel activities of dorsal root ganglion neurons of rats with lumbar disc herniation. Sci. Rep. 6, 38188; doi: 10.1038/srep38188 (2016).

体内研究(In Vivo Assay):

动物模型(Animal Model):LDH rats

实验方法(Assay):Immediately after resolved in NS,AOAA was injected intrathecally at 10μg/kg body weight, once daily for 7 consecutive days. Same volume of NS was used as control.L5-6DRGs from LDH rats after AOAA treatment were collected either for measurement of NaV1.7 and NaV1.8 expression or for patch clamping studies.

 

参考文献

[1] Wallach, D.P. Studies on the GABA pathway. I. The inhibition of γ-aminobutyric acid-α-ketoglutaric acid transaminase in vitro and in vivo by U-7524 (amino-oxyacetic acid). Biochem. Pharmacol. 5(4), 323-331 (1961).

[2] Asimakopoulou, A., Panopoulos, P., Chasapis, C.T., et al. Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE). Br. J. Pharmacol. 169(4), 922-932 (2013).

[3] Löscher, W., Hönack, D., and Gramer, M. Use of inhibitors of gamma-aminobutyric acid (GABA) transaminase for the estimation of GABA turnover in various brain regions of rats: A reevaluation of aminooxyacetic acid. J. Neurochem. 53(6), 1737-1750 (1989)

[4]Löscher, W. A comparative study of the pharmacology of inhibitors of GABA-metabolism. Naunyn Schmiedebergs Arch. Pharmacol. 315(2), 119-128 (1980).

[5] Wang C., Chen H., Zhang M., Zhang J., Wei X., Ying W. (2016). Malate-aspartate shuttle inhibitor aminooxyacetic acid leads to decreased intracellular ATP levels and altered cell cycle of C6 glioma cells by inhibiting glycolysis. Cancer Lett. 378, 1–7. 10.1016/j.canlet.2016.05.001

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MX5301-1MG WSP-1 (H2S Probe)硫化氢荧光探针 1mg
MX5302-1MG WSP-5 (H2S Probe)硫化氢荧光探针 1mg
MX5303-1MG 7-Azido-4-methylcoumarin (AzMC)(H2S Probe)硫化氢荧光探针 1mg
MX5305-50MG Hypotaurine (H2S scavenger)亚牛磺酸(硫化氢清除剂) 50mg
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MX5307-250MG DL-Propargylglycine (hydrochloride) DL-炔丙基甘氨酸盐酸盐 250mg
MX5314-500MG Aminooxyacetic Acid Hemihydrochloride氨氧基乙酸半盐酸盐 500mg
MX3265-100UG Bongkrekic Acid, Triammonium Salt米酵菌酸三胺盐 100μg
MX3266-10MG Decylubiquinone癸基泛醌 10mg

 

AOAA Hemihydrochloride 氨氧基乙酸半盐酸盐


描述

AOAA Hemihydrochloride 氨氧基乙酸半盐酸盐

 

产品标签

AOAA Hemihydrochloride 氨氧基乙酸半盐酸盐;AOA Hemihydrochloride;WSP-1 (Washington State Probe-1);WSP-5;CBS抑制剂; GABA转氨酶抑制剂;CAS NO. 2921-14-4;

产品信息

产品名称

产品编号 规格         价格(元)

Aminooxyacetic Acid Hemihydrochloride (AOAA Hemihydrochloride)

氨氧基乙酸半盐酸盐

MX5314-500MG   

500mg 283
MX5314-1G 1g

423

MX5314-5G 5g

993

产品描述

氨氧基乙酸半盐酸盐(Aminooxyacetic Acid Hemihydrochloride, AOAA Hemihydrochloride)是GABA转氨酶抑制剂(Ki= 9.16μM),诱导大脑内GABA累积[1]。AOAA还能抑制胱硫醚β合成酶(CBS)和胱硫醚γ裂解酶(CSE)活性,IC50分别是8.5μM和1.1μM[2]。AOAA(100mg/kg)降低GABA转氨酶活性,不会对谷氨酸脱羧酶(GAD)活性产生影响,并且能提高大鼠大脑所有区域的GABA水平[3]。AOAA(13mg/kg)还能减低小鼠大脑的GABA转氨酶活性,以及增加GABA水平。AOAA抑制3-巯基丙酸、马钱子碱和戊四氮唑诱导的小鼠癫痫发作,ED50s分别是53、130和85mg/kg,然而,AOAA在烟囱试验中呈现神经毒性(ED50= 62mg/kg),且对小鼠有致命性(LD50=105mg/kg)[4]。AOAA还普遍用作苹果酸-天冬氨酸穿梭(Malate-aspartate shuttle, MAS)抑制剂,抑制C6胶质细胞的胞内ATP水平和改变细胞周期,还能减少糖酵解速率、胞外乳酸和丙酮酸水平[5]。

产品特性

同义名:Carboxymethoxylamine hemihydrochloride, AOAA hemihydrochloride, AOA hemihydrochloride, Aminooxyacetate hemihydrochloride; Aminooxyacetic Acid (hydrochloride);羧甲氧基胺半盐酸盐;羧基甲氧基胺半盐酸盐;氨氧基乙酸半盐酸盐;
CAS NO:2921-14-4 化学名:2-(aminooxy)-acetic acid hemihydrochloride
分子式:C2H5NO3• 1/2HCl

分子量:109.3

纯度:≥95%

外观:固体

溶解性:溶于DMSO(≥10mg/ml)、H2O(≥10mg/ml)、不溶于乙醇
化学结构式:

保存与运输方法

保存:-20℃干燥保存,至少2年有效。

运输:室温运输。

注意事项

1)本品并非商业化的临床药物,仅用作科研用途,不得用作临床诊断或治疗,不得用于食品或药品,绝对禁止用在人身上。

2)为了您的安全和健康,请穿实验服并戴一次性手套操作。

储存液制备

         质量

溶剂体积

浓度

1mg 5mg 10mg
1mM 9.1491 mL 45.7457 mL 91.4913 mL
5mM 1.8298 mL 9.1491 mL 18.2983 mL
10mM 0.9149 mL 4.5746 mL 9.1491 mL

【温馨提示】:请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。储备液置于-80°C密封避光干燥保存,约6个月有效;-20°C密封避光干燥保存,约1个月有效。

使用方法【源自文献,仅作参考】

文献1,Yang B, Su Y, Han S, Chen R, Sun R, Rong K, Long F, Teng H, Zhao J, Liu Q, Qin A. Aminooxyacetic acid hemihydrochloride inhibits osteoclast differentiation and bone resorption by attenuating oxidative phosphorylation. Front Pharmacol. 2022 Sep 30;13:980678. doi: 10.3389/fphar.2022.980678. PMID: 36249744; PMCID: PMC9561130.

体外研究(In Vitro Assay):

细胞类型(Cell type):Bone marrow-derived macrophages (BMMs)

配制方法(Formulation):AOAA was dissolved in phosphate-buffered saline at a concentration of 20 mM at−20°C, and further diluted to working concentration using culture medium.

实验方法(Cell viability assay):BMMs (7 × 103cells/well) were seeded into 96-well plates and cultured in complete α-MEM containing 30 ng/ml M-CSF andAOAA (0, 0.1, 0.2, 0.3, 0.4, and 0.5 mM) for 48 and 96 h.CCK-8 was used to measure cell viability.

体内研究(In Vivo Assay):

动物模型(Animal Model):Ovariectomized mouse model

实验方法(Assay):Twenty-four C57BL/6J mice (females, 11-week-old) were randomly divided into four groups containing six mice each: sham (injected PBS), OVX + PBS (injected PBS), OVX + estrogen (injected 100 ng/kg E2), and OVX + AOAA (injected 5 mg/kg AOAA). The mice were anesthetized with 3% tribromoethanol; next, both the ovaries of all mice except those in the sham group were surgically excised.A week later, the mice received intraperitoneal injections of PBS, E2, or AOAA every 2 days for 6 weeks.

文献2,Yan, J. et al. Inhibition of cystathionine β-synthetase suppresses sodium channel activities of dorsal root ganglion neurons of rats with lumbar disc herniation. Sci. Rep. 6, 38188; doi: 10.1038/srep38188 (2016).

体内研究(In Vivo Assay):

动物模型(Animal Model):LDH rats

实验方法(Assay):Immediately after resolved in NS,AOAA was injected intrathecally at 10μg/kg body weight, once daily for 7 consecutive days. Same volume of NS was used as control.L5-6DRGs from LDH rats after AOAA treatment were collected either for measurement of NaV1.7 and NaV1.8 expression or for patch clamping studies.

 

参考文献

[1] Wallach, D.P. Studies on the GABA pathway. I. The inhibition of γ-aminobutyric acid-α-ketoglutaric acid transaminase in vitro and in vivo by U-7524 (amino-oxyacetic acid). Biochem. Pharmacol. 5(4), 323-331 (1961).

[2] Asimakopoulou, A., Panopoulos, P., Chasapis, C.T., et al. Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE). Br. J. Pharmacol. 169(4), 922-932 (2013).

[3] Löscher, W., Hönack, D., and Gramer, M. Use of inhibitors of gamma-aminobutyric acid (GABA) transaminase for the estimation of GABA turnover in various brain regions of rats: A reevaluation of aminooxyacetic acid. J. Neurochem. 53(6), 1737-1750 (1989)

[4]Löscher, W. A comparative study of the pharmacology of inhibitors of GABA-metabolism. Naunyn Schmiedebergs Arch. Pharmacol. 315(2), 119-128 (1980).

[5] Wang C., Chen H., Zhang M., Zhang J., Wei X., Ying W. (2016). Malate-aspartate shuttle inhibitor aminooxyacetic acid leads to decreased intracellular ATP levels and altered cell cycle of C6 glioma cells by inhibiting glycolysis. Cancer Lett. 378, 1–7. 10.1016/j.canlet.2016.05.001

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2,4-Dichlorophenoxy Acetic Acid (2,4-D) 2,4-二氯苯氧基乙酸


描述

2,4-Dichlorophenoxy Acetic Acid Solution (1mg/ml)  

2,4-二氯苯氧基乙酸母液(2,4-D母液)

 

产品标签

2,4-Dichlorophenoxy Acetic Acid (2,4-D) 2,4-二氯苯氧基乙酸;3-吲哚乙酸(IAA);Plant growth regulator植物生长调节剂;Auxin生长素;CAS:94-75-7;

 

产品信息

产品名称 产品编号 规格 价格(元)
2,4-二氯苯氧基乙酸母液(2,4-D母液) MX7267 100ml 148

 

产品描述

2,4-二氯苯氧基乙酸(2,4-Dichlorophenoxy Acetic Acid, 2,4-D)是一种合成的生长素,是3-吲哚乙酸(IAA)的一种结构类似物,用作一种植物生长调节剂,支持胚胎发生和愈伤组织形成。也是除草剂内的一种活性组分,通过破坏微丝骨架来控制细胞生成和根部延伸。

本品以无菌溶液形式提供,浓度为1mg/ml,达植物细胞培养级别。

 

产品特性

1) CAS NO:94-75-7

2) 同义名:2,4-Dichlorophenoxyacetic acid; 2,4-D;2,4-二氯苯氧乙酸;

3) 分子式:C8H6Cl2O3

4) 分子量:221.04

5) 纯度:≥98%

6) 外观:溶液

8)化学结构:

 

保存与运输方法

保存:2-8℃保存,至少6个月有效。 

运输:冰袋运输。

 

注意事项

1)本品用于植物细胞培养的常用浓度范围是0.01~6mg/L,具体工作浓度请根据实际用途来调整。

2)我司提供冻干粉形式的2,4-D(货号:MX7267-25G),更经济实惠。

3)为了您的安全和健康,请穿实验服并戴一次性手套操作。

 

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生物素-PEG₃-胺


基本信息

产品名称 生物素-PEG₃-胺
英文名称 (+)-Biotin-PEG₃-amine
别名 生物素-PEG3-NH2;N-生物素基-3,6,9-三氧杂十一烷-1,11-二胺;N-[2-[2-[2-(2-氨基乙氧基)乙氧基]乙氧基]乙基]生物素酰胺
英文别名 N-Biotinyl-3,6,9-trioxaundecane-1,11-diamine;N-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethyl]biotinamide;Biotin-PEG3-Amine
应用 Nucleophilic biotinylation reagent for the attachment of cell surface glycosides to ELISA-type surfaces via a hydrophilic spacer/linker
规格或纯度 95%
运输条件 冰袋运输

一般描述

Nucleophilic biotinylation reagent for the attachment of cell surface glycosides to ELISA-type surfaces via a hydrophilic spacer/linker

Nucleophilic biotinylation reagent for the attachment of cell surface glycosides to ELISA-type surfaces via a hydrophilic spacer/linker

相关属性

CAS编号 359860-27-8
敏感性 空气及热敏感
储存温度 2-8°C储存,充氩
MDL号 MFCD09952640
分子量 418.55
分子式 C18H34N4SO5
品牌 金畔生物
PubChem CID 50896259

生物素-PEG₄-叠氮


基本信息

产品名称 生物素-PEG₄-叠氮
英文名称 Biotin-PEG₄-Azide
别名 N-[2-[2-[2-[2-(2-叠氮基乙氧基)乙氧基]乙氧基]乙氧基]乙基]生物素酰胺
英文别名 N-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethyl]biotinamide
规格或纯度 >96.0%(HPLC)
运输条件 超低温冰袋运输

相关属性

CAS编号 1309649-57-7
敏感性 对热敏感
熔点 104 °C
储存温度 -20°C储存
MDL号 MFCD27977501
分子量 488.6
分子式 C20H36N6O6S
品牌 金畔生物
PubChem CID 77078236

α-胺-ω-丙酸四甘醇


基本信息

产品名称 α-胺-ω-丙酸四甘醇
英文名称 α-Amine-ω-propionic acid tetraethylene glycol
别名 3-[2-[2-[2-(2-氨基乙氧基)乙氧基]乙氧基]乙氧基]丙酸
英文别名 (PEO)4-Aminopropionic acid;Tetraethylene glycol amino propionic acid;Amino-PEG4-acid;1-Amino-3,6,9,12-tetraoxapentadecan-15-oic acid;3-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]propionic acid;Amino-PEG-acid;Carboxy-PEG4-amine;CA(PEG)4;NH2-PEG4-COOH
规格或纯度 98%
运输条件 超低温冰袋运输

一般描述

Amino-dPEG4-acid has a primary amine and propionic acid terminating opposite ends of a 16-atoms long (18.0 Å) polyethylene glycol (PEG) spacer. The single molecular weight PEG spacer is discrete (Ð = 1). Moreover, it is highly hydrophilic, and it imparts hydrophilicity to conjugates that incorporate it. Amino-dPEG4-acid is useful in many different applications, including peptide synthesis, surface modification, dendrimer construction, and small molecule modification

Amino-dPEG4-acid has a primary amine and propionic acid terminating opposite ends of a 16-atoms long (18.0 Å) polyethylene glycol (PEG) spacer. The single molecular weight PEG spacer is discrete (Ð = 1). Moreover, it is highly hydrophilic, and it imparts hydrophilicity to conjugates that incorporate it. Amino-dPEG4-acid is useful in many different applications, including peptide synthesis, surface modification, dendrimer construction, and small molecule modification

相关属性

CAS编号 663921-15-1
储存温度 -20°C储存
分子量 265.30
分子式 C11H23NO6
品牌 金畔生物
PubChem CID 22731902