9,10-Anthracenediyl-bis(methylene)dimalonic Acid (ABDA)  9,10-蒽二基-双(亚甲基)二甲酸(单线态氧指示剂)


描述

9,10-Anthracenediyl-bis(methylene)dimalonic Acid (ABDA)  

9,10-蒽二基-双(亚甲基)二甲酸(单线态氧指示

 

产品标签

9,10-Anthracenediyl-bis(methylene)dimalonic Acid; ABDA; ABMDMA; DPBF; [Ru(dpp)3]Cl2;Ru(ddp); SOSG 单线态氧荧光探针;CAS: 307554-62-7;

产品信息

产品名称

产品编号 CAS NO. 规格 价格(元)

9,10-Anthracenediyl-bis(methylene)dimalonic Acid

 (ABDA) 单线态氧指示剂

MX4822-50MG

307554-62-7 50mg

990

MX4822-100MG 307554-62-7 100mg

1980

MX4822-250MG 307554-62-7 250mg

4150

产品描述

9,10-蒽二基-双(亚甲基)二甲酸(9,10-Anthracenediyl-bis(methylene)dimalonic Acid, ABDA),是一款测定单线态氧(1O2)的指示剂,具有比 9,10-蒽二基-二-二丙酸更好的特性。这一水溶性的蒽衍生物与单线态氧反应,光漂白生成对应的内过氧化物(见下图),这一反应通过分光光度法记录400nm处光密度的降低来监测[1-2]

产品特性

CAS NO.:307554-62-7
化学名:α910-dicarboxy-9,10-anthracenedipropanoic acid
同义名:ABMDMA; ABDA; ADMA;
分子式:C22H18O8
分子量:410.37
外观:固体
荧光:λex 380 nm; λem 407 nm in 0.1 M phosphate pH 7.0
纯度:≥95%
溶解性:溶于DMSO(30mg/ml)、H2O

保存与运输方法

保存:-20℃避光干燥保存,至少2年有效。 

运输:冰袋运输。

注意事项

为了您的安全和健康,请穿实验服并戴一次性手套操作。

应用示例(仅作参考)

文献来源:Zhao B, Yin JJ, Bilski PJ, Chignell CF, Roberts JE, He YY. Enhanced photodynamic efficacy towards melanoma cells by encapsulation of Pc4 in silica nanoparticles. Toxicol Appl Pharmacol. 2009;241(2):163-172. Edited by MKBIO. doi: 10.1016/j.jphotobiol.2020.111787. Epub 2020 Jan 11.

实验方法:通过化学探针- 9,10-anthracenediyl-bis(methylene)dimalonic acid (ABMDMA)的光漂白特性来测定光诱导的单线态氧生成。

Fig Photobleaching of 0.15 mM 9,10-anthracenediyl-bis(methylene)dimalonic acid (ABMDMA) by singlet oxygen generated by (i) void silica nanoparticles as control; (ii, iii) 2 μM Pc4SNP and Pc4 water solution. The change in ABMDMA absorption at 400 nm was measured as a function of irradiation time. Inset: absorption spectra of 0.15 mM ABMDMA water solution containing 2 μM Pc4SNP as a function of irradiation times (0 to 360 sec). Values are the means ± SEM (n = 3).

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