LBIS® 尿白蛋白检测试剂盒 自我免疫疾病 肾病研究

自我免疫疾病 肾病研究

LBIS® 尿白蛋白检测试剂盒

白蛋白检测用 ELISA Kit

■ LBIS® Albumin Mouse ELISA Kit

■ LBIS® Albumin Rat ELISA Kit

追加双板试剂盒

标准曲线范围:50~1,000 ng/mL

◆特点

● 短时间测定(总反应时间:2小时2分)

● 可微量样品测定(标准操作法为5μL)

● 使用对环境无害的防腐剂

● 全部试剂均为液体,可直接使用

● 精密的测试精度和告再现性

◆精度测试

● 组内变异(5次重复测定、3个样品): 平均 C.V. 值为 10% 以下

● 组间变异(3次重复测定、3个样品、3天): 平均 C.V. 值为 10% 以下

◆样品:血清或血浆、尿液

 

● 血浆采血推荐使用肝素

● 用本试剂盒配备的缓冲液稀释检体,稀释范围如下:

 

稀释倍数

血浆或血清检体:1万~5万倍

尿液检体:100 倍

 

8W

12W

16w

20w

24w

32w

40w

MRL/lpr,♂

8.9(5.3)

3.7(2.7)

30.1(5.7)

3,504(4,012)

2,100(3,990)

MRL/lpr,♀

2.5(0.6)

4.5(3.6)

2,055(3,244)

435(481)

436(616)

NZBWF1,♀

3.2(3.0)

4.6(2.0)

3.3(2.2)

3.1(1.8)

476(681)

3,471(4,288)

 

 

白蛋白检测试剂盒(免疫比浊法)

Turbidimetric Immuno Assay Kit (TIA Kit)

 

LBIS® 尿白蛋白检测试剂盒 自我免疫疾病 肾病研究

■ LBIS® Albumin-Monkey(S-type)

■ LBIS® Albumin-Rat(S-type)

※ 图片为 LBIS® Albumin-Rat(S-type)

◆特点

● 测试范围

  猴子 2.5~202.5 μg/mL

  小鼠/大鼠 6.17~500 μg/mL

● 样品:尿液或血清

● 对猴子、小鼠、大鼠白蛋白各自使用专用抗体会分别产生特异反应。

● 使用普通的生化学自动分析装置,可短时间(10分钟)测定。

● 测试范围广,再现性高。

● 自定分析装置测试,不受手工操作影响。

● 为日本国内厂商的自动分析装置提供参数。(一部分除外)

◆精度测试(同时测试猴子用、小鼠用、大鼠用)

● 组内变异(5次重复检测、3个样品):平均 C.V. 值为 10% 以下

● 组间变异(3次重复检测、3个样品、4天):平均 C.V. 值为 10% 以下

 

 

参考文献

◆Lbis® 小鼠白蛋白 ELISA试剂的相关参考文献

 

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Podocan Is Expressed in Blood and Adipose Tissue and Correlates Negatively With the Induction of Diabetic Nephropathy ? Yasunori Nio, Mitsugi Okawara, Shoki Okuda, Takanori Matsuo, Naoki Furuyama. Journal of the Endocrine Society, Vol.1, Issue 7, Jul 2017, Pages 772-786,

 

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Ameliorates the Progression of Type 2 Diabetic Nephropathy by Exerting Antioxidative Effects. Ishizawa K., Izawa-Ishizawa Y., Yamano N., Urushihara M., Sakurada T., Imanishi M., Fujii S., Nuno A., Miyamoto L., Kihira Y., Ikeda Y., Kagami S., Kobori H., Tamaki T. PLOS one, 2014

 

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Fibroblast Growth Factor 21 Improves Insulin Resistance and Ameliorates Renal Injury in db/db Mice. Kim HW., Lee JE., Cha JJ., Hyun YY., Kim JE., Lee MH., Song HK., Nam DH., Han JY., Han SY., Han KH., Kang YS. and Cha DR. Endocrinology, Vol.154(9), Sep 2013.

 

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Phycocyanin and phycocyanobilin from Spirulina platensis protect against diabetic nephropathy by inhibiting oxidative stress. Zheng J., Inoguchi T., Sasaki S., Maeda Y., McCarty MF., Fujii M., Ikeda N., Kobayashi K., Sonoda N., Takayanagi R. American Journal of Physiology – Regulatory, Integrative and Comparative Physiology, Vol.304, R110-120, Jun 2013.

 

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◆Lbis® 大鼠白蛋白 ELISA试剂盒相关参考文献

 

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Protective Role of PEDF-Derived Synthetic Peptide Against Experimental Diabetic Nephropathy. Ishibashi Y, Matsui T, Taira J, Higashimoto Y, Yamagishi S. Horm Metab Res. 2016 Sep;48(9):613-9.

 

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A sodium-glucose co-transporter 2 inhibitor empagliflozin prevents abnormality of circadian rhythm of blood pressure in salt-treated obese rats. Takeshige Y, Fujisawa Y, Rahman A, Kittikulsuth W, Nakano D, Mori H, Masaki T, Ohmori K, Kohno M, Ogata H, Nishiyama A. Hypertens Res. 2016 Jun;39(6):415-22.

 

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Effect of ipragliflozin, an SGLT2 inhibitor, on progression of diabetic microvascular complications in spontaneously diabetic Torii fatty rats. Takakura S, Toyoshi T, Hayashizaki Y, Takasu T. Life Sci. 2016 Feb 15;147:125-31.

 

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An Atherogenic Paigen-Diet Aggravates Nephropathy in Type 2 Diabetic OLETF Rats. Masanori Nozako, Takashi Koyama, Chifumi Nagano, Makoto Sato, Satoshi Matsumoto, Kiminobu Mitani, Reiko Yasufuku, Masayuki Kohashi, and Tomohiro Yoshikawa. PLoS One. 2015; 10(11): e0143979.

 

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Oxygenated Static Preservation of Donation after Cardiac Death Liver Grafts Improves Hepatocyte Viability and Function.. Yu J, Murakami M, Aoki T, Jiang B, Jin Z, Koizumi T, Kusano M, Kamijo R, Miyamoto Y, Enami Y, Watanabe M, Otsuka K. Eur Surg Res. 2016;56(1-2):1-18.

 

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Chronic Running Exercise Alleviates Early Progression of Nephropathy with Upregulation of Nitric Oxide Synthases and Suppression of Glycation in Zucker Diabetic Rats. Daisuke Ito, Pengyu Cao, Takaaki Kakihana, Emiko Sato, Chihiro Suda, Yoshikazu Muroya, Yoshiko Ogawa, Gaizun Hu, Tadashi Ishii, Osamu Ito, Masahiro Kohzuki, and Hideyasu Kiyomoto. PLoS One. 2015; 10(9): e0138037.

 

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Effect of ipragliflozin, an SGLT2 inhibitor, on progression of diabetic microvascular complications in spontaneously diabetic Torii fatty rats. Takakura S, Toyoshi T, Hayashizaki Y, Takasu T. Life Sci. Volume 147, 15 February 2016, Pages 125–131

 

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Automated image analysis of a glomerular injury marker desmin in SDT rats treated with losartan. Kakimoto T, Okada K, Hirohashi Y, Relator R, Kawai M, Iguchi T, Fujitaka K, Nishio M, Kato T, Fukunari A, Utsumi H. J Endocrinol, Vol.222(1), p43-51, Jul 2014.

 

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Exercise training upregulates nitric oxide synthases in the kidney of rats with chronic heart failure. Ito D., Ito O., Mori N., Cao P., Suda C., Muroya Y., Hao K., Shimokawa H., Kohzuki M. Clinical and Experimental Pharmacology and Physiology, Vol.40(9), p617-625, Sep 2013.

 

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Sulodexide improves renal function through reduction of vascular endothelial growth factor in type 2 diabetic rats. Cha JJ., Kang YS., Hyun YY., Han SY., Jee YH., Han KH., Han JY., Cha DR. Life Sciences, Vol.92(23), p1118-1124, Jun 2013.

 

11.

Aberrant Activation of the Intrarenal Renin-Angiotensin System in the Developing Kidneys of Type 2 Diabetic Rats. Fan YY., Kobori H., Nakano D., Hitomi H., Mori H., Masaki T., Sun YX., Zhi N., Zhang L., Huang W., Zhu B., Li P. and Nishiyama A. Horm Metab Res, Vol.45(5), p338-343, May 2013.

 

12.

Effects of exercise training on nitric oxide synthase in the kidney of spontaneously hypertensive rats. Ito D, Ito O, Cao P, Mori N, Suda C, Muroya Y, Takashima K, Ito S, Kohzuki M. Clinical and Experimental Pharmacology and Physiology, Vol.40(2), p74-82, Feb 2013.

 

13.

Renal Sympathetic Denervation Suppresses De Novo Podocyte Injury and Albuminuria in Rats With Aortic Regurgitation. Rafiq K, Noma T, Fujisawa Y, Ishihara Y, Arai Y, Nurun Nabi A H M, Suzuki F, Nagai Y, Nakano D, Hitomi H, Kitada K, Urushihara M, Kobori H, Kohno M, Nishiyama A. Circulation,Vol.125, p1402-1413,2012.

 

14.

GLP-1 analog liraglutide protects against oxidative stress and albuminuria in streptozotocin-induced diabetic rats via protein kinase A-mediated inhibition of renal NAD(P)H oxidases. Hendarto H, Inoguchi T, Maeda Y, Ikeda N, Zheng J, Takei R, Yokomizo H, Hirata E, Sonoda N, Takayanagi R. Metabolism – Clinical and Experimental,Vol.61(10), p1422-1434, Oct 2012.

 

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N-type Calcium Channel Inhibition With Cilnidipine Elicits Glomerular Podocyte Protection Independent of Sympathetic Nerve Inhibition. Lei B,Nakano D, Fujisawa Y, Liu Y, Hitomi H, Kobori H, Mori H, Masaki T, Asanuma K, Tomino Y and Nishiyama A. J Pharmacol Sci, Vol.119(4), p359-367, Aug 2012.

 

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Beneficial effect of ubiquinol, the reduced form of coenzyme Q10, on cyclosporine nephrotoxicity. Ishikawa A, Homma Y. Int. braz j urol, Vol.38(2) 2012.

 

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Effect of Eplerenone, a Selective Aldosterone Blocker, on the Development of Diabetic Nephropathy in Type 2 Diabetic Rats . Ahn J H, Hong H C, Cho M J, Kim Y J, Choi H Y, Eun C R, Yang S J, Yoo H J, Kim H Y, Seo J A, Kim S G, Choi K M, Baik S H, Choi D S and Kim N H.  Diabetes Metab J, Vol36(2), p128-135, Apr 2012.

 

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P2X7 receptor antagonism attenuates the hypertension and renal injury in Dahl salt-sensitive rats. X. Ji., Y. Naito., G. Hirokawa., H. Weng., Y. Hiura., R. Takahashi and N. Iwai. Hypertension Research, 35, p173-179 (February 2012)

 

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The effects of iridium on the renal function of female Wistar rats. Iavicoli I, Fontana L, Marinaccio A, Alimonti A, Pino A, Bergamaschi A, Calabrese E J. Ecotoxicology and Environmental Safety, Vol.74(7), p1795-1799, Oct 2011.

 

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Effect of methylmercury administration on choroid plexus function in rats. M. Nakamura., A. Yasutake., M. Fujimura., N. Hachiya and M. Marumoto. Archives of Toxicology Vol. 85, (2011), p911-918,

 

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Renal preservation effect of ubiquinol, the reduced form of coenzyme Q10. A. Ishikawa., H. Kawarazaki., K. Ando., M. Fujita., T. Fujita and Y. Homma. Clinical and Experimental Nephrology Vol.15, Number 1 (2011), p30-33,

 

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Effects of mineralocorticoid receptor blockade on glucocorticoid-induced renal injury in adrenalectomized rats. K. Rafiq., D. Nakano., G. Ihara., H. Hitomi., Y. Fujisawa., N. Ohashi., H. Kobori., Y. Nagai., H. Kiyomoto., M. Kohno and A. Nishiyama. J Hypertens. 2011 February; 29(2): p290-298.

 

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Regression of superficial glomerular podocyte injury in type 2 diabetic rats with overt albuminuria: effect of angiotensin II blockade. Ihara G, Kiyomoto H, Kobori H, Nagai Y, Ohashi N, Hitomi H, Nakano D, Pelisch N, Hara T, Mori T, Ito S, Kohno M and Nishiyamad A. J Hypertens, Vol.28(11), p2289-2298, Nov 2010 .

 

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Visfatin is upregulated in type-2 diabetic rats and targets renal cells. Kang Y S, Song H K, Lee M H, Ko G J, Han J Y, Han S Y, Han K H, Kim H K and Cha D R. Kidney International, Vol.78, p170-181, 2010.

 

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High Salt Intake Elevated Blood Pressure but not Changed Circadian Blood Pressure Rhythm in Otsuka Long-Evans Tokushima Fatty (OLETF) Rat. Matsumoto M, Tsujino T, Naito Y, Sakoda T, Ohyanagi M, Nonaka H and Masuyama T. Clinical and Experimental Hypertension, Vol.31(3) , p271-280, 2009

 

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Cold Preservation of the Liver With Oxygenation by a Two-Layer Method. Odaira,M., Aoki,T., Miyamoto,Y., Yasuhara,R., Jin,Z., Yu,J., Nishino,N., Yamada,K., Kusano,T., Hayashi,K., Yasuda,D., Koizumi,T., Mitamura,K., Enami,Y., Niiya,T., Murai,N., Kato,H., Shimizu,Y., Kamijyo,R., and Kusano, M. Journal of Surgical Research, Volume 152(2), p209-217, 2009.

 

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Effect of Astaxanthin in Combination with α-Tocopherol or Ascorbic Acid against Oxidative Damage in Diabetic ODS Rats. NAKANO M, ONODERA A, SAITO E, TANABE M, YAJIMA K, TAKAHASHI J, CHUYEN N V. Journal of Nutritional Science and Vitaminology, Vol.54(4), p329-334, 2008.

 

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Pioglitazone attenuates diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats. Ko G J, Kang Y S, Han S Y, Lee M H, Song H K, Han K H, Kim H K, Han J Y and Cha D R. Nephrol. Dial. Transplant, Vol23(9), p2750-2760, 2008.

 

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Strict angiotensin blockade prevents the augmentation of intrarenal angiotensin II and podocyte abnormalities in type 2 diabetic rats with microalbuminuria. Nishiyama A, Nakagawa T, Kobori H, Nagai Y, Okada N, Konishi Y, Morikawa T, Okumura M, Meda I, Kiyomoto H, Hosomi N, Mori T, Ito S and Imanishie M. J Hypertens, Vol.26(9), p1849-1859, Sep 2008.

 

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Angiotensin receptor blockers improve insulin resistance in type 2 diabetic rats by modulating adipose tissue. Lee M H, Song H K, Ko G J, Kang Y S, Han S Y, Han K H, Kim H K, Han J Y and Cha D R. Kidney International, Vo.l74, p890-900, 2008.

 

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Cell processing on polyimide surface patterned by rubbing. Matsumoto,N.,Hiruma,H.,Nagaoka,S.,Fujiyama,K.,Kaneko,A., and Kawakami, H.. Polymers for Advanced Technologies, Vol.19(8), p1002-1008, 2008.

 

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Pitavastatin ameliorates albuminuria and renal mesangial expansion by downregulating NOX4 in db/db mice. Fujii M, Inoguchi T, Maeda Y, Sasaki S, Sawada F, Saito R, Kobayashi K, Sumimoto H and Takayanagi R. Kidney International, Vol.72, p473-480, 2007.

 

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Antidiabetic effect of long-term supplementation with Siraitia grosvenori on the spontaneously diabetic Goto-Kakizaki rat. Suzuki, Y.A., Tomoda, M., Murata Y., Inui, H., Sugiura, M., and Nakano, Y. British J Nutrition, Vol.97, p770-775, 2007.

 

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Hepatocyte transplantation from steatotic liver in a rat model. Hayashi, K., Aoki, T., Jin, Z., Wang, H., Nishino, N., Kusano, T., Yasuda, D., Koizumi, T., Enami, Y., and Odaira, M. J Surgical Research, Vol.142, p104-112, 2007

 

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Dietary nitrite inhibits early glomerular injury in streptozotocin-induced diabetic nephropathy in rats. Ohtake, K., Ishiyama, Y., Uchida, H., Muraki, E., and Kobayashi, J. Nitric Oxide, Vol.17, p75-81, 2007.

 

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High-fat diet in low-dose-streptozotocin-treated heminephrectomized rats induces all features of human type 2 diabetic nephropathy: A new rat model of diabetic nephropathy. Sugano M, Yamato H, Hayashi T, Ochiai H, Kakuchi J, Goto S, Nishijima F, Iino N, Kazama J J, Takeuchi T, Mokuda O, Ishikawa T, Okazaki R. Nutrition, Metabolism and Cardiovascular Diseases, Vol.16(7), p477-484, Oct 2006.

 

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Spironolactone ameriolates renal injuary and connective tissue growth factor expression in type II diabetic rats. Han, K.H., Kang, Y.S., Han, S.Y., Jee, Y.H., Lee, M.H., Han, J.Y., Kim, H.K., Kim, Y.S., and Cha, D.R. Kidney International, Vol.70, p111-120, 2006.

 

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Spironolactone prevents diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats. Han,S.Y., Kim, C.H., Kim, H.S., Jee, Y.H., Song, H.K., Lee, M.H., Han, K.H., Kim, H.K., Kang, Y.S., Han, J.Y., Kim, Y.S. and Cha, D.R. J Am Soc Nephrology, Vol.17, p1362-1372, 2006.

 

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Efficient in vivo xenogeneic retroviral vector-mediated gene transduction into human Hepatocytes. Kentaro Emoto, Chise Tateno, Hiroshi Hino, Hironobu Amano, Yasuhiro Imaoka, Kinji Asahina, Toshimasa, Asahara, and Katsutoshi Yoshizato. Human Gene Therapy, Vol.16, p1168-1174, 2005.

 

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In vivo engineering of metabolically active hepatic tissue in a neovascularized subcutaneous cavity. Yokoyama, T., Ohashi, K., Kuge, H., Kanehiro, H., Iwata, H., Yamato, M., and Nakajima, Y. Am J Transplantation, Vol.6, p50-59, 2005.

 

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Effect of retinoic acid in experimental diabetic nephropathy. Han, S.Y., so, G.A., Jee, Y.H., Han, K.H., Kang, Y.S., Kim, H.K., Kang, S.W., Han, D.S., Han, J.Y., and Cha, D.R. Immunol Cell Biol, Vol.82, p568-576, 2004.

 

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Enhanced activity of serum and urinary hyaluronidases in streptozotocin-induced diabetic Wister and GK rats. Ikegami-Kawai, M., Okuda, R., Nemoto, T., Inada, N., and Takahashi, T. Glycobiology, Vol.14, p65-72, 2004.

 


产品列表
产品编号 产品名称 产品规格 产品等级 备注
638-04309 (AKRAL-121) LBIS® Mouse Albumin ELISA kit
LBIS® 小鼠白蛋白 ELISA试剂盒
96 tests
638-31931 (AKRAL-221)LBIS® Mouse Albumin ELISA KIT (2plate type) 96 tests×2
635-04319 (AKRAL-120)LBIS® Rat Albumin ELISA kit
LBIS® 大鼠白蛋白 ELISA试剂盒
96 tests
631-31921 (AKRAL-220)LBIS® Rat Albumin ELISA KIT (2plate type) 96 tests×2
638-25561 (AKRAL-021S)LBIS®  Albumin-Mouse(S-type)
LBIS®  小鼠尿白蛋白检测试剂盒(S型)TIA(含量)
60 tests
634-25301 (AKRAL-020S) LBIS®  Albumin-Rat(S-type)
LBIS®  大鼠尿白蛋白检测试剂盒(S型)TIA(含量)
60 tests

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