4 arm PEG derivatives have multiple reactive groups that can be used to modify proteins, peptides and other materials via their functional groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces. 

Product Introduction

4 arm PEG thiol is one of Nanocs’ reactive multifunctional 4 arm polyethylene glycol (PEG) derivatives. 4 arm PEG thiols have four free sulfhydryl functional groups on each star-shaped PEG core molecule. Thiol functionalized PEG derivatives have reduced sulfhydryl groups that can easily react with maleimide, pyridyldithiol and many other thiol reactive groups. 4 armed PEG thiols have four terminal thiol groups that can be used for crosslinking reaction. Because of their tendency to form disulfide bond, part of these 4 arm PEG thiols may have crosslinked to each other. Reducing process may be necessary if free thiol is a requirement.

4 arm PEG derivatives have multiple reactive groups that can be used to modify proteins, peptides and other materials via their functional groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces. 

Product Introduction

4 arm PEG thiol is one of Nanocs’ reactive multifunctional 4 arm polyethylene glycol (PEG) derivatives. 4 arm PEG thiols have four free sulfhydryl functional groups on each star-shaped PEG core molecule. Thiol functionalized PEG derivatives have reduced sulfhydryl groups that can easily react with maleimide, pyridyldithiol and many other thiol reactive groups. 4 armed PEG thiols have four terminal thiol groups that can be used for crosslinking reaction. Because of their tendency to form disulfide bond, part of these 4 arm PEG thiols may have crosslinked to each other. Reducing process may be necessary if free thiol is a requirement.