基本信息
| 产品名称 | 聚乙二醇 |
|---|---|
| 英文名称 | PEG；Poly(ethylene glycol) |
| 别名 | 聚氧乙烯；PEG；聚（乙二醇） |
| 英文别名 | PEG |
| 应用 | 通常用于修饰治疗蛋白和多肽，以增加其溶解性和降低其毒性。 更环保地选择性氟化乙醯胺的氟化溶剂 |
| 规格或纯度 | average Mn 6000 |
| 运输条件 | 常规运输 |
| 生化机理 | Polyethylene glycol (PEG) is a condensation polymer of ethylene oxide and water. It enhances the refolding of extracted proteins. This enables characterization of crystallized proteins. |
一般描述
有轻微特殊气味。微有吸湿性。遇热易熔化。溶于水和乙醇
聚乙二醇（PEG）是一种亲水性的聚合物。它可以通过环氧乙烷的阴离子开环聚合而被轻易的合成为不同的分子量和并带有各种端基。当交联成网络时，PEG可具有高的含水量，形成“水凝胶”。水凝胶的形成可通过电离辐射交联PEG或通过PEG大分子单体与反应性链端的共价交联而引发。PEG引其不会触发免疫反应而成为一种适合于生物学应用的材料。
通常用于修饰治疗蛋白和多肽，以增加其溶解性和降低其毒性。
更环保地选择性氟化乙醯胺的氟化溶剂
Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks PEG can have high water content, forming “hydrogels”. Hydrogel formation can be initiated by either crosslinking PEG by ionizing radiation or by covalent crosslinking of PEG macromers with reactive chain ends. PEG is a suitable material for biological applications because it does not trigger an immune response.
application：
Polyethylene glycol is used in the modification of therapeutic proteins and peptides to enhance its solubility. It is also used in the fabrication of bioactive and immuno isolating barriers for encapsulation of cells. In Gas chromatorgraphy, it is used as a polar stationary phase. It is used as mold release agent and lubricant in fabricating elastomers.
安全信息
| 个人防护设备 | Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
|---|---|
| WGK | 1 |
| Merck Index | 7568 |
| 闪点（摄氏） | 171°C |
相关属性
| CAS编号 | 25322-68-3 |
|---|---|
| 敏感性 | 对湿度敏感 |
| 折光率 | 1.4590 |
| 熔点 | 58 – 67 °C |
| 溶解性 | Soluble in water and aromatic hydrocarbons. Slightly and aliphatic hydrocarbons |
| 储存温度 | 干燥 |
| MDL号 | MFCD00081839 |
| 分子式 | HO(CH2CH2O)nH |
| 品牌 | 金畔生物 |
| 备注 | 10g卖完停产，不再备货 |
